Electromechanical coupling of waves in nerve fibres

  title={Electromechanical coupling of waves in nerve fibres},
  author={J. Engelbrecht and Tanel Peets and Kert Tamm},
  journal={Biomechanics and Modeling in Mechanobiology},
The propagation of an action potential (AP) in a nerve fibre is accompanied by mechanical and thermal effects. In this paper, an attempt is made to build up a mathematical model which couples the AP with a possible pressure wave (PW) in the axoplasm and waves in the nerve fibre wall (longitudinal—LW and transverse—TW) made of a lipid bilayer (biomembrane). A system of differential equations includes the governing equations of single waves with coupling forces between them. The single equations… 

Mathematics of Nerve Signals

In this chapter, a coupled model for the nerve signal is presented in the form of a nonlinear system of partial differential equations which is solved numerically by making use of the Fourier transform based pseudospectral method.

On mechanisms of electromechanophysiological interactions between the components of signals in axons

An overview is presented on experimental results and possible mechanisms of electromechanophysiological couplings which govern the signal formation in axons, and a proposed mathematical model is modified reflecting the possible physical explanation of these interactions.

On a Model for Nerve Impulse Generation Mediated by Electromechanical Processes

An electromechanical model for the nerve is considered, in which mechanical forces are assumed to be generated by fluid flow through the nerve membrane, and hence control the net charge stored in the membrane capacitor.

Neuromechanical modulation of transmembrane voltage in a model of a nerve.

An electromechanical model of a nerve is proposed in order to advance understanding of how mechanical forces and thermodynamics also regulate neural electrical activities and it is shown that the mechanical properties of membranes affect the localization of the transmembrane potential.

Primary and secondary components of nerve signals

The action potential propagating in a nerve fibre generates accompanying mechanical and thermal effects. The whole signal is therefore an ensemble which includes primary and secondary components. The

Continuous signaling pathways instability in an electromechanical coupled model for biomembranes and nerves

Abstract Information processing is a basic part of life and, presumably, the nervous system’s primary purpose. Neurons perform a variety of tasks that collect useful information from the organism’s

Criteria for modelling wave phenomena in complex systems:the case of signals in nerves

In this paper the wave phenomena in nerves are characterized from the viewpoint of complexity and interdisciplinarity, followed by the analysis of principles and criteria in the modelling of biological systems.

On the Physical Background of Nerve Pulse Propagation: Heat and Energy

Abstract Recent studies have revealed the complex structure of nerve signals in axons. Besides the electrical signal, mechanical and thermal effects are also detected in many experimental studies. In



On the complexity of signal propagation in nerve fibres

It is proposed that three processes – the propagation of an action potential and mechanical waves in the biomembrane and in the axoplasmatic fluid – be united into a general model with additional interaction forces for reflecting coupling, which results in the emerging of a mutually interacting ensemble of waves.

Mechanical surface waves accompany action potential propagation.

A model for mechanical displacements as arising from the driving of surface wave modes in which potential energy is stored in elastic properties of the neuronal membrane and cytoskeleton while kinetic energy is carried by the axoplasmic fluid is presented.


It is suggested that the propagation of the action potential is accompanied by anAxoplasmic pressure pulse propagating in the axoplasm along the axon length, causing their accelerated activation and inactivation and increasing peak channel conductance.

On modelling of physical effects accompanying the propagation of action potentials in nerve fibres

In this paper an attempt is made to unify various mathematical models which describe the signal propagation in nerve fibres based on the coupling of action potentials with mechanical waves in a nerve fibre.

A macromolecular approach to excitation phenomena: mechanical and thermal changes in nerve during excitation.

  • I. Tasaki
  • Biology, Chemistry
    Physiological chemistry and physics and medical NMR
  • 1988
A physicochemical theory is described that explains macromolecular transitions between two stable states of the nerve membrane and the mechanism of nerve excitation is explained on a physicochemical basis.

On the action potential as a propagating density pulse and the role of anesthetics

The thermodynamic theory of nerve pulses suggests a explanation for the famous Meyer-Overton rule that states that the critical anesthetic dose is linearly related to the solubility of the drug in the membranes.

Theory of electromechanical effects in nerve

An investigation into two well-known electrostatic properties of dielectrics, electrostriction and piezoelectricity, in the context of the nerve membrane is undertaken, which predicts a few percent change in axon dimensions for voltage- and space-clamped axons.