Electromagnetic Field Stimulation Potentiates Endogenous Myelin Repair by Recruiting Subventricular Neural Stem Cells in an Experimental Model of White Matter Demyelination

@article{Sherafat2012ElectromagneticFS,
  title={Electromagnetic Field Stimulation Potentiates Endogenous Myelin Repair by Recruiting Subventricular Neural Stem Cells in an Experimental Model of White Matter Demyelination},
  author={Mohammad Amin Sherafat and Motahare Heibatollahi and Somayeh Mongabadi and Fatemeh Moradi and Mohammad Reza Javan and Abolhassan Ahmadiani},
  journal={Journal of Molecular Neuroscience},
  year={2012},
  volume={48},
  pages={144-153}
}
Electromagnetic fields (EMFs) may affect the endogenous neural stem cells within the brain. The aim of this study was to assess the effects of EMFs on the process of toxin-induced demyelination and subsequent remyelination. Demyelination was induced using local injection of lysophosphatidylcholine within the corpus callosum of adult female Sprague–Dawley rats. EMFs (60 Hz; 0.7 mT) were applied for 2 h twice a day for 7, 14, or 28 days postlesion. BrdU labeling and immunostaining against nestin… 
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