Electrolytic lesions of the ventral subiculum weakly alter spatial memory but potentiate amphetamine-induced locomotion

@article{Riegert2004ElectrolyticLO,
  title={Electrolytic lesions of the ventral subiculum weakly alter spatial memory but potentiate amphetamine-induced locomotion},
  author={C{\'e}line Riegert and Rodrigue Galani and Sarah Heilig and Christine Lazarus and Brigitte Cosquer and J. C. Cassel},
  journal={Behavioural Brain Research},
  year={2004},
  volume={152},
  pages={23-34}
}
View on Elsevier
doi.org
17 Citations
Highly Influential Citations
1
Background Citations
7
Methods Citations
1
Results Citations
4

17 Citations

Citation Type

Citation Type

Combined lesions of GABAergic and cholinergic septal neurons increase locomotor activity and potentiate the locomotor response to amphetamine
Post insult enriched housing improves the 8-arm radial maze performance but not the Morris water maze task in ventral subicular lesioned rats
Reinforcing Effect of Optogenetic Stimulation of Dorsal Subiculum
TLDR
It is demonstrated that mice placed in custom built operant nose poke chambers will nose poke for optogenetic stimulation of the dSUB and this reinforcing effect was significantly greater than baseline nose poking rates or poking for a light cue and was dependent on the frequency of stimulation, with increased frequency correlating with increased self-stimulation rates.
Modulation by the dorsal, but not the ventral, hippocampus of the expression of behavioural sensitization to amphetamine.
TLDR
It is found that reversible inhibition by lidocaine of DH, but not VH, blocks the expression of behavioural sensitization to amphetamine, suggesting that, in individuals well habituated to the drug-associated context, DH but notVH would play a key role in the maintenance of drug abuse.
Environmental enrichment improved cognitive deficits more in peri-adolescent than in adult rats after postnatal monosodium glutamate treatment.
TLDR
Investigation of the positive regulatory effect of short-term exposure to EE on establishing functional recovery in monosodium glutamate (MSG)-induced obese rats suggests the therapeutic potential of EE paradigm in prevention of cognitive disorders.
Contribution of the dorsal subiculum to memory for temporal order and novelty detection using objects, odors, or spatial locations in the rat
Transplantation of hippocampal cell lines restore spatial learning in rats with ventral subicular lesions.
TLDR
The H3-GFP transplants mediated recovery of cognitive functions in VSL rats supports the notion of graft meditated host regeneration and functional recovery through trophic support, although these mechanisms require further investigation.
Opiate withdrawal modifies synaptic plasticity in subicular–nucleus accumbens pathway in vivo
Role of the Ventral Hippocampus in Exploration and Ventral Hippocampal Parvalbumin Neurons in Behaviors relevant to Schizophrenia
TLDR
Overall, these experiments provide support for the role of the vHPC-NAc pathway in mediating exploratory behavior in novel environments, but it remains inconclusive whether dysregulated vH PC activity due to the loss of parvalbumin neurons leads to behaviors associated with schizophrenia.
Neuronal Mechanisms Mediating Acute Food Deprivation-Induced Reinstatement of Heroin Seeking
TLDR
The current results support existing models that suggest a critical role for DA and glutamate transmission, and the interaction between the two systems, in the reinstatement of drug seeking.
...
1
2
...

References

SHOWING 1-10 OF 52 REFERENCES
Ibotenate Lesions of Hippocampus and/or Subiculum: Dissociating Components of Allocentric Spatial Learning
TLDR
The behavioural findings indicated that both the hippocampus and subiculum lesions caused impairment to the initial postoperative acquisition of place navigation but did not prevent eventual learning to levels of performance almost as effective as those of controls, suggesting that total hippocampal cell loss may cause a dual deficit: a slower rate of place learning and a separate navigational impairment.
Lesions of the rat postsubiculum impair performance on spatial tasks.
Loss of hippocampal CA1 neurons and learning impairment in subicular lesioned rats
Spatial Location Learning in Mice with Ibotenate Lesions of Entorhinal Cortex or Subiculum
TLDR
Results indicated that mice with ibotenate lesions of the EC or SUB were impaired in postoperative acquisition of the spatial discrimination task, making more reference, but not working memory, errors and displaying fewer first correct response trials than sham-operated control mice.
Effects of enriched postoperative housing conditions on spatial memory deficits in rats with selective lesions of either the hippocampus, subiculum or entorhinal cortex.
TLDR
The present results indicate that the structures within the hippocampal formation are not similarly involved in spatial learning and memory processes and in the management of navigational demands of the radial maze, and enriched conditions may enhance the spared spatial abilities of some lesioned rats thus promoting functional recovery.
The effects of NMDA‐induced retrohippocampal lesions on performance of four spatial memory tasks known to be sensitive to hippocampal damage in the rat
Four separate cohorts of rats were employed to examine the effects of cytotoxic retrohippocampal lesions in four spatial memory tasks which are known to be sensitive to direct hippocampal damage…
Retrograde Amnesia and Memory Reactivation in Rats with Ibotenate Lesions to the Hippocampus or Subiculum
  • J. Bolhuis, C. Stewart, E. Forrest
  • Psychology, Biology
    The Quarterly journal of experimental psychology. B, Comparative and physiological psychology
  • 1994
TLDR
The results indicate that selective hippocampal formation lesions can cause deficits in retrieval but do not reveal a time-dependent gradient of memory consolidation.
Potentiation of amphetamine-induced locomotor activity following NMDA-induced retrohippocampal neuronal loss in the rat
TLDR
The present results are consistent with the suggestion that cell loss within the retrohippocampal region could affect the functional response of nucleus accumbens to amphetamine and the possible implications for schizophrenia.
Selective lesions of the entorhinal cortex, the hippocampus, or the fimbria-fornix in rats: a comparison of effects on spontaneous and amphetamine-induced locomotion
TLDR
It is shown that lesions of the fimbria-fornix, the hippocampus, and of the entorhinal cortex have different effects on spontaneous and amphetamine-induced hyperactivity, as they also have on learning and memory tasks.
Heterogeneity of the hippocampus: effects of subfield lesions on locomotion elicited by dopaminergic agonists
...
1
2
3
4
5
...