Electrogenicity of sodium/L-glutamate cotransport in rabbit renal brush-border membranes: a reevaluation.

@article{Heinz1988ElectrogenicityOS,
  title={Electrogenicity of sodium/L-glutamate cotransport in rabbit renal brush-border membranes: a reevaluation.},
  author={Erich Heinz and D L Sommerfeld and Rolf K. H. Kinne},
  journal={Biochimica et biophysica acta},
  year={1988},
  volume={937 2},
  pages={
          300-8
        }
}
The Kinetic Mechanism of the Glutamate–Aspartate Carrier in Rat Intestinal Brush-Border Membrane Vesicles: The Role of Potassium
TLDR
The results indicate that the ordered sodium–sodium glutamate mechanism is not altered by potassium, and that the activation is probably exerted on both the rate determining steps of the transport process.
Electrogenic Properties of the Epithelial and Neuronal High Affinity Glutamate Transporter (*)
TLDR
A detailed stoichiometric and kinetic analysis of EAAC1 expressed in Xenopus laevis oocytes demonstrates that under conditions where the electrochemical gradients for these ions are disrupted,EAAC1 runs in reverse, a transport mode which is of pathologic importance.
Characterization of anionic amino acid transport systems in mouse mammary gland.
TLDR
Although neutral amino acids weakly inhibited the uptake of L-glutamate, there was no evidence for the heterogeneity of anionic amino acid transport system.
Regulation of taurine transport in Ehrlich ascites tumor cells
TLDR
It is concluded that the swelling-induced activation of the taurine leak pathway involves a release of arachidonic acid from the membrane phospholipids and an increased oxidation of aracheric acid into leukotrienes via the 5-lipoxygenase pathway.
Molecular characteristics of mammalian and insect amino acid transporters: implications for amino acid homeostasis.
TLDR
The molecular characteristics of K(+)-coupled amino acid transporters in the larval lepidopteran insect midgut are investigated to gain insights into the K-coupling mechanism and into amino acid and K+ homeostasis in insects.
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References

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Hydrogen ion cotransport by the renal brush border glutamate transporter.
TLDR
The results indicate that H+ is cotransported with glutamate and suggest the possibility that, in the absence of internal K+, H+ can also fulfill the requirement for a countertransported ion.
Reconstitution and partial purification of several Na+ cotransport systems from renal brush-border membranes. Properties of the L-glutamate transporter in proteoliposomes.
TLDR
In the proteoliposomes, Na+ cotransport systems for D-glucose, acidic and neutral amino acids, and mono- and dicarboxylic acids were demonstrated by showing that due to an inwardly directed Na+ gradient the substrate concentrations in the proteosomes increased significantly over their respective equilibrium values.
Stoichiometry of Cotransport Systems a
  • R. J. Turner
  • Biology
    Annals of the New York Academy of Sciences
  • 1985
TLDR
The experimental methods currently employed for measuring stoichiometries are discussed, an illustration of the effective use of the thermodynamic principles of coupled transport in a biological system is given, and an discussion of the interplay between the kinetic and thermodynamic properties of the transporter determines its functioning in situ.
A rapid method for the preparation of microvilli from rabbit kidney.
TLDR
Marker enzymes for other subcellular components showed the preparation to be essentially free of mitochondria and to be less contaminated with endoplasmic reticulum and baso-lateral plasma membranes than are conventional brush-border preparations.