Electrogenicity of sodium/L-glutamate cotransport in rabbit renal brush-border membranes: a reevaluation.

@article{Heinz1988ElectrogenicityOS,
  title={Electrogenicity of sodium/L-glutamate cotransport in rabbit renal brush-border membranes: a reevaluation.},
  author={Erich Heinz and D L Sommerfeld and Rolf K. H. Kinne},
  journal={Biochimica et biophysica acta},
  year={1988},
  volume={937 2},
  pages={
          300-8
        }
}
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The Kinetic Mechanism of the Glutamate–Aspartate Carrier in Rat Intestinal Brush-Border Membrane Vesicles: The Role of Potassium
TLDR
The results indicate that the ordered sodium–sodium glutamate mechanism is not altered by potassium, and that the activation is probably exerted on both the rate determining steps of the transport process.
Both Na+ and Cl- gradients energize NaCl/L-glutamate cotransport in lobster hepatopancreatic brush border membrane vesicles.
Characterization of Na(+)-dependent L-glutamate transport in canine erythrocytes.
Electrogenic Properties of the Epithelial and Neuronal High Affinity Glutamate Transporter (*)
TLDR
A detailed stoichiometric and kinetic analysis of EAAC1 expressed in Xenopus laevis oocytes demonstrates that under conditions where the electrochemical gradients for these ions are disrupted,EAAC1 runs in reverse, a transport mode which is of pathologic importance.
Reconstitution into liposomes of the B degrees -like glutamine-neutral amino acid transporter from renal cell plasma membrane.
The transport of acidic amino acids and their analogues across monolayers of human intestinal absorptive (Caco-2) cells in vitro.
Characterization of anionic amino acid transport systems in mouse mammary gland.
TLDR
Although neutral amino acids weakly inhibited the uptake of L-glutamate, there was no evidence for the heterogeneity of anionic amino acid transport system.
Regulation of taurine transport in Ehrlich ascites tumor cells
TLDR
It is concluded that the swelling-induced activation of the taurine leak pathway involves a release of arachidonic acid from the membrane phospholipids and an increased oxidation of aracheric acid into leukotrienes via the 5-lipoxygenase pathway.
Molecular characteristics of mammalian and insect amino acid transporters: implications for amino acid homeostasis.
TLDR
The molecular characteristics of K(+)-coupled amino acid transporters in the larval lepidopteran insect midgut are investigated to gain insights into the K-coupling mechanism and into amino acid and K+ homeostasis in insects.
The glutamate and neutral amino acid transporter family: physiological and pharmacological implications.
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References

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Hydrogen ion cotransport by the renal brush border glutamate transporter.
TLDR
The results indicate that H+ is cotransported with glutamate and suggest the possibility that, in the absence of internal K+, H+ can also fulfill the requirement for a countertransported ion.
Effect of K+ and H+ on sodium/citrate cotransport in renal brush-border vesicles.
The effects of potassium and membrane potential on sodium-dependent glutamic acid uptake.
Reconstitution and partial purification of several Na+ cotransport systems from renal brush-border membranes. Properties of the L-glutamate transporter in proteoliposomes.
TLDR
In the proteoliposomes, Na+ cotransport systems for D-glucose, acidic and neutral amino acids, and mono- and dicarboxylic acids were demonstrated by showing that due to an inwardly directed Na+ gradient the substrate concentrations in the proteosomes increased significantly over their respective equilibrium values.
Stoichiometry of Cotransport Systems a
  • R. J. Turner
  • Biology
    Annals of the New York Academy of Sciences
  • 1985
TLDR
The experimental methods currently employed for measuring stoichiometries are discussed, an illustration of the effective use of the thermodynamic principles of coupled transport in a biological system is given, and an discussion of the interplay between the kinetic and thermodynamic properties of the transporter determines its functioning in situ.
Sodium gradient-dependent L-glutamate transport in renal brush border membrane vesicles. Effect of an intravesicular > extravesicular potassium gradient.
Chromatofocussing and centrifugal reconstitution as tools for the separation and characterization of the Na+-cotransport systems of the brush-border membrane.
Protein measurement with the Folin phenol reagent.
A rapid method for the preparation of microvilli from rabbit kidney.
TLDR
Marker enzymes for other subcellular components showed the preparation to be essentially free of mitochondria and to be less contaminated with endoplasmic reticulum and baso-lateral plasma membranes than are conventional brush-border preparations.
Sodium gradient-dependent L-glutamate transport in renal brush border membrane vesicles. Evidence for an electroneutral mechanism.