Electrogenic transport of neutral and dibasic amino acids in a cultured opossum kidney cell line (OK)

@article{Schwegler1989ElectrogenicTO,
  title={Electrogenic transport of neutral and dibasic amino acids in a cultured opossum kidney cell line (OK)},
  author={Johann S. Schwegler and Almut Heuner and Stefan Silbernagl},
  journal={Pfl{\"u}gers Archiv},
  year={1989},
  volume={414},
  pages={543-550}
}
A study has been made of electrogenic cellular uptake of amino acids resulting in the depolarization of cell membrane potential (PDm) in confluent monolayers of an established opossum kidney (OK) cell line using conventional and pH-selective microelectrodes. Apical superfusion of neutral and dibasic amino acids rapidly depolarized the cell membrane, while application of acidic amino acids had no effect on PDm. The depolarization in response toL-phenylalanine andL-arginine was stereoselective… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Na +gradientdependent glycine uptake in basolateral membrane vesicles from dog kid

  • JS Schwegler, A Heuner, S Silbernagl
  • Am J Physiol
  • 1988

Parathyroid hormone inhibits phosphate transport in OK cells but not in LLCPK 1 and JTC12 . P 3 cells

  • G Stange, H Muter
  • Am J Physiol
  • 1987

The effect of phenylalanine on intracellular pH and sodium activity in proximal tubule cells of the frog kidney

  • RT Miller, AS Pollock, DG Warnock
  • Pfliigers Arch
  • 1987

Evidence for a single common Na +dependent transport system for alanine , glutamine , leucine and phenylalanine in brushborder membrane vesicles from bovine kidney

  • H Murer
  • Biochim Biophys Acta
  • 1986

Similar Papers

Loading similar papers…