Electrogenic Cl− secretion does not occur in the ileum of the Australian common brushtail possum, Trichosurus vulpecula, due to low levels of expression of the NaK2Cl cotransporter, NKCC1

@article{Bartolo2009ElectrogenicCS,
  title={Electrogenic Cl− secretion does not occur in the ileum of the Australian common brushtail possum, Trichosurus vulpecula, due to low levels of expression of the NaK2Cl cotransporter, NKCC1},
  author={Ray C. Bartolo and Natalie Harfoot and Mike Gill and Kristy Demmers and Bernie McLeod and A. Grant Butt},
  journal={Journal of Comparative Physiology B},
  year={2009},
  volume={179},
  pages={997-1010}
}
The colon of the brushtail possum does not have an electrogenic secretory response. Given the functional significance of electrogenic Cl− secretion in the intestine of eutherian mammals, we have investigated the secretory response in the small intestine of this marsupial. In the Ussing chamber cAMP-dependent secretagogues stimulated a sustained increase in ileal short-circuit current (Isc), whereas Ca2+-dependent secretagogues induced a transient increase. Both the responses were inhibited by… CONTINUE READING

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