Electrogenerated chemiluminescence DNA biosensor based on hairpin DNA probe labeled with ruthenium complex.

@article{Zhang2008ElectrogeneratedCD,
  title={Electrogenerated chemiluminescence DNA biosensor based on hairpin DNA probe labeled with ruthenium complex.},
  author={Jing Zhang and Honglan Qi and Yan Li and Jia Yang and Qiang Gao and Chengxiao Zhang},
  journal={Analytical chemistry},
  year={2008},
  volume={80 8},
  pages={2888-94}
}
A highly selective electrogenerated chemiluminescence (ECL) biosensor for the detection of target single-strand DNA (ss-DNA) was developed using hairpin DNA as the recognition element and ruthenium complex as the signal-producing compound. The ECL-based DNA biosensor was fabricated by self-assembling the ECL probe of thiolated hairpin DNA tagged with ruthenium complex on the surface of a gold electrode. In the absence of target ss-DNA, the ECL probe immobilized on the surface of the electrode… CONTINUE READING

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