Electrodiffusive Model for Astrocytic and Neuronal Ion Concentration Dynamics

@article{Halnes2013ElectrodiffusiveMF,
  title={Electrodiffusive Model for Astrocytic and Neuronal Ion Concentration Dynamics},
  author={Geir Halnes and Ivar {\O}stby and Klas H. Pettersen and Stig W. Omholt and Gaute T. Einevoll},
  journal={PLoS Computational Biology},
  year={2013},
  volume={9}
}
The cable equation is a proper framework for modeling electrical neural signalling that takes place at a timescale at which the ionic concentrations vary little. However, in neural tissue there are also key dynamic processes that occur at longer timescales. For example, endured periods of intense neural signaling may cause the local extracellular K+-concentration to increase by several millimolars. The clearance of this excess K+ depends partly on diffusion in the extracellular space, partly on… Expand
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