Electrocorticogram changes during corpus callosotomy for uncontrolled symptomatic generalized epilepsy.


We report a 19-year-old man who presented to our facility with medically intractable, symptomatic generalized epilepsy manifesting as generalized tonic-clonic seizures (GTCs). Before he underwent an anterior callosotomy (6 cm), these seizures, which he had experienced for 11 years, seemed to have a left-sided focal origin. Intraoperatively, no epileptiform discharges were found on the electrocorticogram (ECoG) performed prior to sectioning, but more than 10 left-sided seizures were recorded after sectioning. In the 10 years since surgery, the patient's seizures have remained generalized; however, the frequency and severity of the seizures have decreased. These findings indicate that the presence of electrocorticographic seizures, as measured by ECoG immediately following callosotomy, may not predict a poor surgical outcome, even though such a finding might be indicative of epileptogenicity in general.

DOI: 10.1016/j.jocn.2009.02.022

Cite this paper

@article{Shyu2010ElectrocorticogramCD, title={Electrocorticogram changes during corpus callosotomy for uncontrolled symptomatic generalized epilepsy.}, author={H Y Shyu and Ji-Ho Lin and Shang-Yeong Kwan and Kai-Ping Chang and C Yiu and Tai-Tong Wong}, journal={Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia}, year={2010}, volume={17 1}, pages={132-4} }