Electroconvulsive treatment: Effects on phospholipase C activity and GTP binding activity in rat brain

The effect of electroconvulsive treatment (ECT) on activities of phospholipase C hydrolyzing phosphatidylinositol (PI-PLC) and phosphatidylinositol 4,5-bisphosphate (PIP2-PLC) and guanosine-5′-(3-O-thio)triphosphate (GTPγ S) binding activity were examined in membrane and cytosol fractions from four discrete areas (prefrontal cortex, hippocampus, striatum… CONTINUE READING