Electroconvulsive shock treatments enhance responsiveness of forebrain neurons to serotonin.

@article{Montigny1984ElectroconvulsiveST,
  title={Electroconvulsive shock treatments enhance responsiveness of forebrain neurons to serotonin.},
  author={Claude de Montigny},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1984},
  volume={228 1},
  pages={
          230-4
        }
}
Electroconvulsive therapy remains one of the most effective treatments of major depression. The effect of electroconvulsive shocks (ECSs) on the responsiveness of hippocampal pyramidal neurons to serotonin, norepinephrine, gamma-aminobutyric acid and 5-methoxydimethyltryptamine was studied in rats pretreated with one or six ECSs. Control rats were given subconvulsive shocks. Microiontophoretic experiments were conducted 36 hr after the last shock in urethane-anesthetized or low cerveau isol… CONTINUE READING

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