Electroconvulsive shock in rats: changes in superoxide dismutase and glutathione peroxidase activity.

@article{Erakovi2000ElectroconvulsiveSI,
  title={Electroconvulsive shock in rats: changes in superoxide dismutase and glutathione peroxidase activity.},
  author={Vesna Erakovi{\'c} and Gordana Župan and Jadranka Varljen and Senka Rado{\vs}evi{\'c} and Ante Simoni{\'c}},
  journal={Brain research. Molecular brain research},
  year={2000},
  volume={76 2},
  pages={266-74}
}
Seizures trigger a variety of biochemical processes including an influx of extracellular Ca(2+), activation of membrane phospholipases, liberation of free fatty acids, diacylglycerols, eicosanoids, lipid peroxides and free radicals. These lipid metabolites along with abnormal ion homeostasis may be involved in cell injury and cell death. The aim of this study was to determine brain antioxidant enzyme activities in rats with electroconvulsive shock (ECS)-induced seizures. ECS, single or repeated… CONTINUE READING

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