Electrochemotherapy for cutaneous and subcutaneous tumor lesions: a novel therapeutic approach

  title={Electrochemotherapy for cutaneous and subcutaneous tumor lesions: a novel therapeutic approach},
  author={A. Testori and G. Tosti and C. Martinoli and G. Spadola and F. Cataldo and F. Verrecchia and F. Baldini and M. Mosconi and J. Soteldo and I. Tedeschi and C. Passoni and C. Pari and Alessandra di Pietro and P. Ferrucci},
  journal={Dermatologic Therapy},
  • A. Testori, G. Tosti, +11 authors P. Ferrucci
  • Published 2010
  • Medicine
  • Dermatologic Therapy
  • Electroporation uses pulsed, high‐intensity electric fields to temporarily increase cell membrane permeability by creation of pores, through which small molecules, such as chemotherapeutic agents, can diffuse inside cells before they reseal. The combination of electroporation with the administration of otherwise low‐permeant cytotoxic drugs is known as electrochemotherapy (ECT). The two most commonly used drugs are bleomycin and cisplatin. ECT has already been proven to be effective in diverse… CONTINUE READING
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