Electrochemotherapy as an adjunct or alternative to other treatments for unresectable or in-transit melanoma

@article{Mller2009ElectrochemotherapyAA,
  title={Electrochemotherapy as an adjunct or alternative to other treatments for unresectable or in-transit melanoma},
  author={Mecker G. M{\"o}ller and Slawomir Salwa and D. Soden and Gerald C O'sullivan},
  journal={Expert Review of Anticancer Therapy},
  year={2009},
  volume={9},
  pages={1611 - 1630}
}
Treatment of recurrent or in-transit unresectable melanoma continues to be a major therapeutic challenge. Electrochemotherapy (ECT) is a therapeutic option for those patients whose lesions are not suitable for surgical resection and who have exhausted all other treatment modalities. ECT combines electroporation of tumor cells with the administration either of intravenous or intratumoral antineoplastic drugs, such as bleomycin or cisplatin. The cell membranes are thus rendered permeant to these… 

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omplete regression of melanoma skin etastases after electrochemotherapy plus pilimumab treatment : an unusual clinical

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A case of an advanced melanoma in which a sequential treatment with ECT plus ipilimumab achieved a complete clinical response of multiple cutaneous etastases, with unusual vitiligo-like lesions as the final utcome is described.

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