Electrochemically amplified detection for lipopolysaccharide using ferrocenylboronic acid.

@article{Kato2007ElectrochemicallyAD,
  title={Electrochemically amplified detection for lipopolysaccharide using ferrocenylboronic acid.},
  author={Dai Kato and Seiichiro Iijima and Ryoji Kurita and Yukari Sato and Jianbo Jia and Soichi Yabuki and Fumio Mizutani and Osamu Niwa},
  journal={Biosensors & bioelectronics},
  year={2007},
  volume={22 7},
  pages={1527-31}
}
A novel electrochemical technique for lipopolysaccharide (LPS) detection has been developed using a combination of ferrocenylboronic acid derivatives and an enzyme-modified electrode. The enzyme-modified electrode was constructed from a gold electrode modified with a bovine serum albumin membrane containing diaphorase. Ferrocenylboronic acid derivatives are oxidized on the electrode, and then regenerated by a diaphorase-catalyzed reaction in the presence of NADH. The consumption/regeneration… CONTINUE READING