Electrochemical synthesis of azanucleoside derivatives using a lithium perchlorate-nitromethane system.

Abstract

We have developed a highly efficient synthetic method for azanucleosides using a lithium perchlorate-nitromethane reaction medium, allowing direct and exclusive installation of various nucleophiles, including protected nucleobases into prolinol derivatives at the preferred 5-position.

DOI: 10.1039/c3cc43273d

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Cite this paper

@article{Kim2013ElectrochemicalSO, title={Electrochemical synthesis of azanucleoside derivatives using a lithium perchlorate-nitromethane system.}, author={Shokaku Kim and Takao Shoji and Yoshikazu Kitano and Kazuhiro Chiba}, journal={Chemical communications}, year={2013}, volume={49 58}, pages={6525-7} }