Electrochemical multianalyte immunoassays using an array-based sensor.

  title={Electrochemical multianalyte immunoassays using an array-based sensor.},
  author={Michael S Wilson and Weiyan Nie},
  journal={Analytical chemistry},
  volume={78 8},
A novel amperometric biosensor for performing simultaneous electrochemical multianalyte immunoassays is described. The sensor consisted of eight iridium oxide sensing electrodes (0.78 mm(2) each), an iridium counter electrode, and a Ag/AgCl reference electrode patterned on a glass substrate. Four different capture antibodies were immobilized on the sensing electrodes via adsorption. Quantification of proteins was achieved using an ELISA in which the electrochemical oxidation of enzyme-generated… CONTINUE READING


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