Electrochemical immunosensor for sensitive determination of transforming growth factor (TGF) - β1 in urine.

@article{SnchezTirado2017ElectrochemicalIF,
  title={Electrochemical immunosensor for sensitive determination of transforming growth factor (TGF) - β1 in urine.},
  author={Esther S{\'a}nchez-Tirado and Gonzalo Mart{\'i}nez-Garc{\'i}a and Araceli Gonz{\'a}lez-Cort{\'e}s and Paloma Y{\'a}{\~n}ez-Sede{\~n}o and Jos{\'e} Manuel Pingarr{\'o}n},
  journal={Biosensors & bioelectronics},
  year={2017},
  volume={88},
  pages={9-14}
}
The first amperometric immunosensor for the quantification of TGF-β1, a cytokine proposed as a biomarker for patients having or at risk for renal disease, is described in this work. The immunosensor design involves disposable devices using carboxylic acid-functionalized magnetic microparticles supported onto screen-printed carbon electrodes and covalent immobilization of the specific antibody for TGF-β1 using Mix&Go polymer. A sandwich-type immunoassay was performed using biotin-anti-TGF and… CONTINUE READING

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