Electrochemical immunosensor for interferon-γ based on disposable ITO detector and HRP-antibody-conjugated nano gold as signal tag.

@article{Zhang2016ElectrochemicalIF,
  title={Electrochemical immunosensor for interferon-γ based on disposable ITO detector and HRP-antibody-conjugated nano gold as signal tag.},
  author={Yaru Zhang and Bin Zhang and Xiao-li Ye and Yuqi Yan and Langhuan Huang and Zhenyou Jiang and Shaozao Tan and Xiang Cai},
  journal={Materials science & engineering. C, Materials for biological applications},
  year={2016},
  volume={59},
  pages={577-584}
}
Tuberculosis is the most frequent cause of infection-related death worldwide. A new disposable electrochemical immunosensor with low cost and simple fabrication was proposed to detect interferon-γ (IFN-γ). Diallyldimethylammonium chloride (PDDA) and Au nanoparticle (AuNP) composite were used to provide an efficient biointerface, horseradish peroxidase (HRP)-labeled antibody-conjugated AuNP (HRP-Ab2-AuNP) bioconjugates were used as a novel signal tag. The large amounts of HRP on the signal tag… CONTINUE READING