Electrochemical and spectral studies of the reactions of aquocobalamin with nitric oxide and nitrite ion.

@article{Zheng2002ElectrochemicalAS,
  title={Electrochemical and spectral studies of the reactions of aquocobalamin with nitric oxide and nitrite ion.},
  author={Donghong Zheng and Lei Yan and Ronald L. Birke},
  journal={Inorganic chemistry},
  year={2002},
  volume={41 9},
  pages={2548-55}
}
Electrochemistry and Raman spectroscopy have shown that aquocob(III)alamin (Cbl(III)) can be reduced by nitric oxide (NO) to form Cbl(II) on an electrode surface. The Cbl(II) formed in this way can bind NO to form nitrosyl-cobalamin, Cbl(II)-NO, which is reduced to form Cbl(I) at about -1.0 V vs a KCl saturated Ag/AgCl reference electrode. In addition, nitrite was found to bind both Cbl(III) and Cbl(II) and a binding constant of 3.5 x 10(2) M(-1) was measured for (NO(2)-Cbl(II))(1-). UV-vis… CONTINUE READING