Electrochemical and in vitro evaluation of the redox-properties of kynurenine species.

@article{Giles2003ElectrochemicalAI,
  title={Electrochemical and in vitro evaluation of the redox-properties of kynurenine species.},
  author={Gregory I. Giles and Catriona A. Collins and T. W. Stone and Claus Jacob},
  journal={Biochemical and biophysical research communications},
  year={2003},
  volume={300 3},
  pages={
          719-24
        }
}
Kynurenines are formed as part of the tryptophan metabolism and are known to exhibit pro- and anti-oxidant activities in vitro. The mapping of these biological redox-systems and identification of potential in vivo targets are therefore of great interest in cellular physiology. Here the redox-behavior of different kynurenines and anthranilic acids is evaluated electrochemically and compared to that of simple model compounds. Electrochemical results are correlated with the activity of these… CONTINUE READING

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