Electrocatalytic detection of pathogenic DNA sequences and antibiotic resistance markers.

  title={Electrocatalytic detection of pathogenic DNA sequences and antibiotic resistance markers.},
  author={Melissa A Lapierre and Meaghan O'Keefe and Bradford J Taft and Shana O. Kelley},
  journal={Analytical chemistry},
  volume={75 22},
The detection of specific DNA sequences using electrochemical readout would permit the rapid and inexpensive detection and identification of bacterial pathogens. A new assay developed for this purpose is described that harnesses a sensitive electrocatalytic process to monitor DNA hybridization. Two sequences belonging to the pathogenic microbe Helicobacter pylori are used to demonstrate the versatility and specificity of the assay: one that codes for an unique H. pylori protein and one that… CONTINUE READING


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