Electroacupuncture inhibits phosphorylation of spinal phosphatidylinositol 3-kinase/Akt in a carrageenan-induced inflammatory rat model

@article{Kim2012ElectroacupunctureIP,
  title={Electroacupuncture inhibits phosphorylation of spinal phosphatidylinositol 3-kinase/Akt in a carrageenan-induced inflammatory rat model},
  author={Ha Neui Kim and Yoonjung Kim and Ji yeon Jang and Hwa Kyoung Shin and Byung Tae Choi},
  journal={Brain Research Bulletin},
  year={2012},
  volume={87},
  pages={199-204}
}
We investigated the changes of pain-related spinal signaling pathway after electroacupuncture (EA) stimulation in a carrageenan-induced rat model. EA stimulation (2Hz, 1mA) was needle-delivered for 30 min at acupoints corresponding to Zusanli and Sanyinjiao 3 h after carrageenan injection. Thermal and mechanical sensitivity of the hindpaw induced by carrageenan was strongly inhibited by EA stimulation. Phosphorylation of extracellular signal-regulated kinase, phosphatidylinositol 3-kinase (PI3K… CONTINUE READING
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