Electroacupuncture inhibits CB1 upregulation induced by ethanol withdrawal in mice

@article{EscosteguyNeto2012ElectroacupunctureIC,
  title={Electroacupuncture inhibits CB1 upregulation induced by ethanol withdrawal in mice},
  author={Jo{\~a}o Carlos Escosteguy-Neto and Paula Fallopa and Patr{\'i}cia Varela and Renato Filev and Jair Guilherme Santos-Junior},
  journal={Neurochemistry International},
  year={2012},
  volume={61},
  pages={277-285}
}
CB1R play a role in alcohol withdrawal and in some effects of acupuncture. Interestingly, acupuncture has been used to alleviate alcohol withdrawal. Here, we investigated electroacupuncture (EA) effects during ethanol withdrawal on CB1R immunoreactivity. Male Swiss mice were daily injected with ethanol (2g/kg, i.p) (EtOH group), for 21 days. EA was performed daily during 4 days of ethanol withdrawal. The stimuli of 2 or 100 Hz were provided in two acupoints combination: Ea1 [(ST-36/Zusanli) and… CONTINUE READING

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