Electroacupuncture improves cognitive deficits associated with AMPK activation in SAMP8 mice

@article{Dong2014ElectroacupunctureIC,
  title={Electroacupuncture improves cognitive deficits associated with AMPK activation in SAMP8 mice},
  author={Wei-Guo Dong and Wanqing Guo and Xuehua Zheng and Feng Wang and Yue Chen and Wenguang Zhang and Hong Shi},
  journal={Metabolic Brain Disease},
  year={2014},
  volume={30},
  pages={777-784}
}
Perturbations of brain energy metabolism are involved in Alzheimer’s disease (AD). Adenosine monophosphate-activated kinase (AMPK) is a master energy sensor that monitors the levels of key energy metabolites. Electroacupuncture (EA) has demonstrated therapeutic potential for the treatment of AD. The effects of EA on cognitive functions and the changes of AMPK and its phosphorylated form (p-AMPK) expression were investigated in senescence-accelerated mouse prone 8 (SAMP8) mice. Cognitive… CONTINUE READING