Electroacupuncture Ameliorates Learning and Memory via Activation of the CREB Signaling Pathway in the Hippocampus to Attenuate Apoptosis after Cerebral Hypoperfusion

@inproceedings{Han2013ElectroacupunctureAL,
  title={Electroacupuncture Ameliorates Learning and Memory via Activation of the CREB Signaling Pathway in the Hippocampus to Attenuate Apoptosis after Cerebral Hypoperfusion},
  author={Xiao-Hua Han and Xiuxiu Zhao and Min Lu and Fang Liu and Feng Guo and Jinghui Zhang and Xiaolin Huang},
  booktitle={Evidence-based complementary and alternative medicine : eCAM},
  year={2013}
}
Studies have shown that electroacupuncture (EA) ameliorates learning and memory after ischemic injury. However, there have been few studies elucidating the mechanisms of EA on learning and memory in cerebral hypoperfusion. In this study, we explored the cAMP response element-binding protein (CREB) signaling pathway-mediated antiapoptotic action involved in EA-induced improvement of learning and memory. EA at GV20 and GV14 acupoints was applied in cerebral hypoperfusion rats. A Morris water maze… CONTINUE READING