Electrically evoked skin vasodilatation: a quantitative test of nociceptor function in man.

@article{Westerman1987ElectricallyES,
  title={Electrically evoked skin vasodilatation: a quantitative test of nociceptor function in man.},
  author={R. A. Westerman and Adrian Low and A. V. Pratt and J. S. M. Hutchinson and J{\'a}nos Szolcs{\'a}nyi and W. Magerl and Hermann Otto Handwerker and Wlodzimierz M. Kozak},
  journal={Clinical and experimental neurology},
  year={1987},
  volume={23},
  pages={81-9}
}
Direct stimulation of intact forearm skin affects adjacent microvascular blood flux. Pulses of current, known to activate C-fibres effectively, were applied over a period of 1-16 seconds at 2 Hz using transcutaneous stimulation. An increase of up to 50% was observed in skin microvascular blood flux. Increased blood flux correlated well with increasingly painful sensations. Some subjects responded to one or two pulses at 2 Hz, 0.5 ms in duration and 150 volts. A response onset latency of 4-15 s… CONTINUE READING

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