Electrical synapses and their functional interactions with chemical synapses

@article{Pereda2014ElectricalSA,
  title={Electrical synapses and their functional interactions with chemical synapses},
  author={A. Pereda},
  journal={Nature Reviews Neuroscience},
  year={2014},
  volume={15},
  pages={250-263}
}
  • A. Pereda
  • Published 2014
  • Biology, Medicine
  • Nature Reviews Neuroscience
  • Brain function relies on the ability of neurons to communicate with each other. Interneuronal communication primarily takes place at synapses, where information from one neuron is rapidly conveyed to a second neuron. There are two main modalities of synaptic transmission: chemical and electrical. Far from functioning independently and serving unrelated functions, mounting evidence indicates that these two modalities of synaptic transmission closely interact, both during development and in the… CONTINUE READING
    267 Citations

    Figures and Topics from this paper

    The interplay between electrical and chemical synaptogenesis
    • 8
    How do electrical synapses regulate their strength?
    • 3
    Functional contributions of electrical synapses in sensory and motor networks
    • L. Szczupak
    • Computer Science, Medicine
    • Current Opinion in Neurobiology
    • 2016
    • 9
    Two Forms of Electrical Transmission Between Neurons
    • 9
    • PDF
    Evolutionary origins of chemical synapses.
    A genetic basis for molecular asymmetry at vertebrate electrical synapses
    • 6
    • Highly Influenced
    Electrical synapses and the development of inhibitory circuits in the thalamus
    • 23
    Developmental functions of electrical synapses
    • A. Pereda
    • Biology, Medicine
    • The Journal of physiology
    • 2016
    • 4

    References

    SHOWING 1-10 OF 202 REFERENCES
    Chemical synaptic activity modulates nearby electrical synapses
    • M. Smith, A. Pereda
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 2003
    • 75
    • PDF
    Electrical synapses between Gaba-Releasing interneurons
    • 431
    Gap junctions
    • 432
    Molecular and Functional Asymmetry at a Vertebrate Electrical Synapse
    • 60
    • PDF
    Restless AMPA receptors: implications for synaptic transmission and plasticity
    • 99
    • PDF