Electrical stimulation of the midbrain tectum enhances dopamine release in the frontal cortex.

@article{Cuadra2000ElectricalSO,
  title={Electrical stimulation of the midbrain tectum enhances dopamine release in the frontal cortex.},
  author={Gabriel Ricardo Cuadra and Alejandra Zurita and Carlos Eduardo Macedo and V{\'i}ctor Alejandro Molina and Marcus Lira Brand{\~a}o},
  journal={Brain research bulletin},
  year={2000},
  volume={52 5},
  pages={413-8}
}
One widely used animal model of anxiety is the electrical stimulation of a given structure supposed to be involved in the neural circuitry underlying emotional behavior. Indeed, electrical stimulation of midbrain structures with substrates for the processing of fear-like responses, such as the dorsal periaqueductal gray matter (DPAG) or the inferior colliculus (IC), produces behavioral, sensorial and autonomic responses very similar to the defense reactions observed in environmental threatening… CONTINUE READING

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