Electrical restitution and cardiac fibrillation.

  title={Electrical restitution and cardiac fibrillation.},
  author={James N. Weiss and Peng-Sheng Chen and Zhilin Qu and Hrayr S. Karagueuzian and Shin-Fong Lin and Alan Garfinkel},
  journal={Journal of cardiovascular electrophysiology},
  volume={13 3},
Combined experimental and theoretical work has shown that restitution properties of the cardiac action potential duration and conduction velocity contribute to breakup of reentrant wavefronts during cardiac fibrillation independent of preexisting electrophysiologic heterogeneities in the tissue. Developing therapies that favorably alter these cardiac electrical restitution properties are a promising new approach to preventing fibrillation. 

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