Electrical remodeling in a canine model of ischemic cardiomyopathy.

@article{Liu2007ElectricalRI,
  title={Electrical remodeling in a canine model of ischemic cardiomyopathy.},
  author={Xian-sheng Liu and Min Jiang and Mei Zhang and Daniel Kwok-Lun Tang and Henry F. Clemo and Robert S. D. Higgins and Gea-Ny Tseng},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2007},
  volume={292 1},
  pages={
          H560-71
        }
}
The nature of electrical remodeling in a canine model of ischemic cardiomyopathy (ICM; induced by repetitive intracoronary microembolizations) that exhibits spontaneous ventricular tachycardia is not entirely clear. We used the patch-clamp technique to record action potentials and ionic currents of left ventricular myocytes isolated from the region affected by microembolizations. We also used the immunoblot technique to examine channel subunit expression in adjacent affected tissue. Ventricular… CONTINUE READING

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