Electrical interactions between a real ventricular cell and an anisotropic two-dimensional sheet of model cells.

@article{Wang2000ElectricalIB,
  title={Electrical interactions between a real ventricular cell and an anisotropic two-dimensional sheet of model cells.},
  author={Yikai Wang and Rajiv B. Kumar and Mary B. Wagner and Ronald Wilders and David A. Golod and William N. Goolsby and Ronald W. Joyner},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2000},
  volume={278 2},
  pages={H452-60}
}
We have extended our "coupling clamp" technique, in which we couple a real cell to a real-time simulation of a model cell, to now incorporate a real cardiac cell as the central element of a two-dimensional sheet of model cells, in which the coupling conductances may be different in the x and y directions and a specific region of lack of coupling conductance may serve as a resistive barrier. We stimulated the real cell in the central location and determined the critical size of the real cell for… CONTINUE READING
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