Electrical coupling between endothelial cells and smooth muscle cells in hamster feed arteries: role in vasomotor control.

@article{Emerson2000ElectricalCB,
  title={Electrical coupling between endothelial cells and smooth muscle cells in hamster feed arteries: role in vasomotor control.},
  author={Geoffrey G Emerson and Steven S Segal},
  journal={Circulation research},
  year={2000},
  volume={87 6},
  pages={474-9}
}
Endothelial cells (ECs) govern smooth muscle cell (SMC) tone via the release of paracrine factors (eg, NO and metabolites of arachidonic acid). We tested the hypothesis that ECs can promote SMC relaxation or contraction via direct electrical coupling. Vessels (resting diameter, 57+/-3 microm; length, 4 mm) were isolated, cannulated, and pressurized (75 mm Hg; 37 degrees C). Two microelectrodes were used to simultaneously impale 2 cells (ECs or SMCs) in the vessel wall separated by 500 microm… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
118 Citations
42 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 118 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Similar Papers

Loading similar papers…