Electric gene transfer to the liver following systemic administration of plasmid DNA

@article{Liu2002ElectricGT,
  title={Electric gene transfer to the liver following systemic administration of plasmid DNA},
  author={Feng Liu and Leaf Huang},
  journal={Gene Therapy},
  year={2002},
  volume={9},
  pages={1116-1119}
}
Recently, there has been an increasing level of interest in electroporation for gene delivery due to the site-specific nature of the delivery, as well as the high efficiency of the method. Electroporation involves the application of a pulsed electric field to cells to enhance cell permeability, resulting in the transit of exogenous polynucleotide across the cytoplasmic membrane. Electroporation is traditionally performed by locally injecting DNA to the site of interest followed by the… CONTINUE READING
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DNA into liver

  • RW Malone
  • Hum Gene Ther
  • 1994

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