Elective transfer of two embryos: Reduction of multiple gestations while maintaining high pregnancy rates

@article{DowlingLacey2006ElectiveTO,
  title={Elective transfer of two embryos: Reduction of multiple gestations while maintaining high pregnancy rates},
  author={Donna Dowling-Lacey and Estella Lynn Jones and Jacob F. Mayer and Silvina M. Bocca and Laurel Stadtmauer and Sergio Oehninger},
  journal={Journal of Assisted Reproduction and Genetics},
  year={2006},
  volume={24},
  pages={11-15}
}
Purpose: To determine if the elective transfer of two embryos reduced the incidence of multiple gestations while maintaining high pregnancy rates. Methods: IVF patients and recipients of oocyte donation with an elective day-3 transfer of 2 or 3 embryos were studied. Result(s): In IVF, the elective transfer of 2 embryos resulted in similar pregnancy rate but significantly reduced the overall incidence of multiple gestations (20% versus 39%) when compared to the elective transfer of 3 embryos… 
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9 Citations
Background Citations
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9 Citations

Economic evaluation of elective single-embryo transfer with subsequent single frozen embryo transfer in an in vitro fertilization/intracytoplasmic sperm injection program.
Factors Influencing Pregnancy Outcome Following Slow Cooling Cryoembryo Transfer and Risk of Multiple Conception
Impact of male age on the outcome of assisted reproductive technology cycles using donor oocytes.
Does storage time influence postthaw survival and pregnancy outcome? An analysis of 11,768 cryopreserved human embryos.
Gonadotrophin ovulation induction and enhancement outcomes: analysis of more than 1400 cycles.
Impact of serum estradiol levels on the implantation rate of cleavage stage cryopreserved-thawed embryos transferred in programmed cycles with exogenous hormonal replacement
TLDR
Neither late follicular phase serum E2 nor the early E2/P4 ratio were able to predict implantation or pregnancy outcome of day-3 cryopreserved-thawed embryos transferred in artificially programmed cycles.
Does the degree of hypothalamic-pituitary-ovarian recovery after oral contraceptive pills affect outcomes of IVF/ICSI cycles receiving GnRH-antagonist adjuvant therapy in women over 35 years of age?
TLDR
Gonadotropin serum levels after OCP treatment provide information for optimization of supplementation with LH in GnRH-antagonist IVF cycles in women over age 35.
The search for biomarkers of human embryo developmental potential in IVF: a comprehensive proteomic approach.
TLDR
It is demonstrated that peptide/protein profiles from the culture medium during early human in vitro development can discriminate embryos with highest and lowest implantation competence following uterine transfer.
A cross-sectional evaluation of the first cohort of young adults conceived by in vitro fertilization in the United States.

References

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TLDR
In women under 36 years of age, transferring one fresh embryo and then, if needed, one frozen-and-thawed embryo dramatically reduces the rate of multiple births while achieving a rate of live births that is not substantially lower than the rate that is achievable with a double-embryo transfer.
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TLDR
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TLDR
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TLDR
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TLDR
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