Elastosis perforans serpiginosa-like pseudoxanthoma elasticum in a child with severe Moya Moya disease.

@article{Meyer2005ElastosisPS,
  title={Elastosis perforans serpiginosa-like pseudoxanthoma elasticum in a child with severe Moya Moya disease.},
  author={Stefanie Lee Meyer and Livia Zanardo and W E Kaminski and Per Horn and Gerd Schmitz and Ulr{\'i}ch Hohenleutner and Werner Herrmann and M{\'i}chael Landthaler and Thomas Joesf Vogt},
  journal={The British journal of dermatology},
  year={2005},
  volume={153 2},
  pages={
          431-4
        }
}
A 2-year-old girl with Moya Moya disease who had relapsing cerebrovascular strokes presented with loose skin folds, 'chicken' skin appearance and perforating elastosis serpiginosa-like lesions in the genitocrural region. Histologically, calcified material perforating the epidermis and adjacent short curled and mineralized elastic fibres suggested a variant of pseudoxanthoma elasticum (PXE). As PXE is known to be caused by various mutations in the transmembrane transporter ABCC6 gene, we… CONTINUE READING
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