Elastically Coupled Two-Level Systems as a Model for Biopolymer Extensibility

@inproceedings{Rief1998ElasticallyCT,
  title={Elastically Coupled Two-Level Systems as a Model for Biopolymer Extensibility},
  author={Matthias Rief and J. M. Fern{\'a}ndez and Hermann Eduard Gaub},
  year={1998}
}
We present Monte Carlo simulations for the elasticity of biopolymers consisting of segments that can undergo conformational transitions. Based on the thermodynamics of an elastically coupled twolevel system, the probability for a transition and a related change in length of each segment was calculated. Good agreement between this model description and measured data was found for both the polysaccharide dextran where the conformational changes are fast and the muscle protein titin where the… CONTINUE READING
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