Elastic network normal modes provide a basis for protein structure refinement.


It is well recognized that thermal motions of atoms in the protein native state, the fluctuations about the minimum of the global free energy, are well reproduced by the simple elastic network models (ENMs) such as the anisotropic network model (ANM). Elastic network models represent protein dynamics as vibrations of a network of nodes (usually represented… (More)
DOI: 10.1063/1.4710986


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