Elastic large muscular vessel wall engineered with bone marrow‑derived cells under pulsatile stimulation in a bioreactor.

@article{Zhicheng2015ElasticLM,
  title={Elastic large muscular vessel wall engineered with bone marrow‑derived cells under pulsatile stimulation in a bioreactor.},
  author={Xu Zhicheng and QUN ZHANG and Li Hong},
  journal={Molecular medicine reports},
  year={2015},
  volume={12 4},
  pages={
          6005-12
        }
}
Bone marrow‑derived cells (BMCs) have demonstrated their ability to differentiate into multiple cell lineages and may be a promising cell source for vascular tissue engineering. Although much progress has been made in the engineering of small blood vessels (<6 mm in diameter) with biodegradable materials such as polyglycolic acid (PGA), it remains a challenge to engineer large vessels (>6 mm in diameter) due to unsatisfactory biomechanical properties. The present study was to engineered an… CONTINUE READING

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