Elastic fibers in scar tissue

@article{Roten1996ElasticFI,
  title={Elastic fibers in scar tissue},
  author={S V Roten and S Bhat and Jag Bhawan},
  journal={Journal of Cutaneous Pathology},
  year={1996},
  volume={23}
}
The capacity of the skin to be stretched and to return to its resting position is correlated to the quantity and to the quality of the elastic fiber network. Although elastic fibers have been demonstrated in scars, the time course of their appearance in scars and their role in scar elasticity has not been elucidated. A study was therefore undertaken to evaluate the elastic fiber network in scars. 
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The integrity of the elastic fiber network is a strong determinant of the skin’s elasticity, resilience, quality, and texture and its importance is particularly exemplified by the severity of skin impairment in various genetic disorders that affect elastin expression in the dermis.
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    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging
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The aim of the study was to assess the percentage of elastic fibres between superficial and deep fascia.
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The literature is reviewed to summarize the role of elastin in the formation scars, as well as treatment via therapeutic lasers, using ablative, nonablative, and fractional laser devices for the treatment of scars.
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Marked disruption and aberrant regulation of elastic fibres in early striae gravidarum
Striae gravidarum (SG), or ‘stretch marks’ of pregnancy, begin as erythematous streaks, and mature over months to years to become permanent scar‐like bands that may be hypopigmented, atrophic and lax.
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This chapter considers the mechanical and biochemical roles of elastin in elastic tissues and the subsequent disease phenotypes that result from the degradation and loss of Elastin, the development and success of current elastIn based biomaterials including sources ofElastin for tissue engineering and their application, and vascular constructs that the laboratory has developed from recombinant human tropoelastin.
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The goal of this study was to ascertain the density of elastic tissue fibers in DF in an effort to investigate whether this provides an insight into its etiopathogenesis.
Treatment of Burn and Surgical Wounds With Recombinant Human Tropoelastin Produces New Elastin Fibers in Scars
  • Hua Xie, L. Lucchesi, K. Gregory
  • Medicine
    Journal of burn care & research : official publication of the American Burn Association
  • 2017
TLDR
This is the first report demonstrating that subcutaneous injections of TE into surgical and burn injuries can safely produce new elastin fibers in scars, and despite the development of new elASTin fibers, skin flexibility was not improved.
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References

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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