Elastic fibers in scar tissue
@article{Roten1996ElasticFI, title={Elastic fibers in scar tissue}, author={S V Roten and S Bhat and Jag Bhawan}, journal={Journal of Cutaneous Pathology}, year={1996}, volume={23} }
The capacity of the skin to be stretched and to return to its resting position is correlated to the quantity and to the quality of the elastic fiber network. Although elastic fibers have been demonstrated in scars, the time course of their appearance in scars and their role in scar elasticity has not been elucidated. A study was therefore undertaken to evaluate the elastic fiber network in scars.
61 Citations
The Role of Elastin in Wound Healing and Dermal Substitute Design
- Biology
- 2013
The integrity of the elastic fiber network is a strong determinant of the skin’s elasticity, resilience, quality, and texture and its importance is particularly exemplified by the severity of skin impairment in various genetic disorders that affect elastin expression in the dermis.
Elastic Fibres in the subcutaneous tissue: Is there a difference between superficial and muscular fascia? A cadaver study
- MedicineSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging
- 2021
The aim of the study was to assess the percentage of elastic fibres between superficial and deep fascia.
Elastic fiber pattern in scleroderma/morphea
- MedicineJournal of cutaneous pathology
- 2009
A systematic study of the elastic fiber pattern correlated with CD34 expression is reported in scleroderma/morphea, characterized by expansion of the dermis with thickened collagen bundles and loss of CD34+ dermal dendrocytes.
The Role of Elastic Fibers in Scar Formation and Treatment
- MedicineDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
- 2017
The literature is reviewed to summarize the role of elastin in the formation scars, as well as treatment via therapeutic lasers, using ablative, nonablative, and fractional laser devices for the treatment of scars.
Mechanical forces induce scar remodeling. Study in non-pressure-treated versus pressure-treated hypertrophic scars.
- Medicine, BiologyThe American journal of pathology
- 1999
Advances in biomimetic regeneration of elastic matrix structures
- Engineering, BiologyDrug Delivery and Translational Research
- 2012
An overview of the role and importance of elastin and elastic matrix in soft tissues, the challenges to elastic matrix generation in vitro and to regenerative elastic matrix repair in vivo, current biomolecular strategies to enhanceElastin deposition and matrix assembly, and the need to concurrently inhibit proteolytic matrix disruption for improving the quantity and quality ofElastogenesis are provided.
Marked disruption and aberrant regulation of elastic fibres in early striae gravidarum
- BiologyThe British journal of dermatology
- 2015
Striae gravidarum (SG), or ‘stretch marks’ of pregnancy, begin as erythematous streaks, and mature over months to years to become permanent scar‐like bands that may be hypopigmented, atrophic and lax.
Elastin Based Constructs
- Biology, Engineering
- 2011
This chapter considers the mechanical and biochemical roles of elastin in elastic tissues and the subsequent disease phenotypes that result from the degradation and loss of Elastin, the development and success of current elastIn based biomaterials including sources ofElastin for tissue engineering and their application, and vascular constructs that the laboratory has developed from recombinant human tropoelastin.
Morphometric analyses of elastic tissue fibers in dermatofibroma: clues to etiopathogenesis?
- MedicineJournal of cutaneous pathology
- 2009
The goal of this study was to ascertain the density of elastic tissue fibers in DF in an effort to investigate whether this provides an insight into its etiopathogenesis.
Treatment of Burn and Surgical Wounds With Recombinant Human Tropoelastin Produces New Elastin Fibers in Scars
- MedicineJournal of burn care & research : official publication of the American Burn Association
- 2017
This is the first report demonstrating that subcutaneous injections of TE into surgical and burn injuries can safely produce new elastin fibers in scars, and despite the development of new elASTin fibers, skin flexibility was not improved.
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Elastic fibers in scar tissue: scanning and transmission electron microscopic studies
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Findings suggestive of newly synthesized elastic fibers were seen in some hypertrophic scar tissue and SEM and TEM indicated that there is elastogenesis in scar tissue.
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Several staining methods are worked out which enable to obtain a selective staining of all the elastic and pre-elastic fibers with noStaining of the background by using in the staining solution polyphenols like: pyrogallol, (+) catechin, tannic acid and others.