• Corpus ID: 57316873

El microbioma humano. Su papel en la salud y en algunas enfermedades

  title={El microbioma humano. Su papel en la salud y en algunas enfermedades},
  author={Ra{\'u}l Ariza-Andraca and Marisol Garc{\'i}a-Ronquillo},
  journal={Cirugia Y Cirujanos},
The human microbiome is formed by the microorganisms along with their genetic elements and their interactions with environment. The microbiota is essential for the normal function of some organs. Recently the microbiome has been implicated in the pathogenic mechanisms of certain diseases such as obesity, diabetes and digestive functional disorders. The study of this complex elements will allow a better understanding of microbiome as well as that of the related diseases. All Rights Reserved… 

The Microbiome and the Epigenetics of Diabetes Mellitus

The modification of the GM and its relation with DM2 is described to describe the increased risk of this disease is associated with changes in the amount of Bacteroides/Clostridium in the Firmicutes/Bacteroidetes ratio of people having DM.

Gut Microbiota and Obesity: Prebiotic and Probiotic Effects

This chapter looks at defining the established relationship between probiotics, prebiotics and gut microbiota that develop in obese people and people of normal weight, with the aim of providing future dietary recommendations to treat this medical condition.

Maternal Prenatal Microbiome and Infant’s Immune System at the Origins of the Development of Health and Disease

Bacteria are microorganisms that have managed to colonize the vast majority of land surfaces, showing great adaptability, and hypotheses have been raised that affirm the human being's participation in the development of health and the onset of the disease.



The gut microbiota—a clinical perspective on lessons learned

  • F. Shanahan
  • Medicine, Biology
    Nature Reviews Gastroenterology &Hepatology
  • 2012
The microbiota is both a target for drug therapy and a repository for drug discovery, and its secrets promise the realization of personalized medicine and nutrition, and will change and improve conventional dietary management.

A microbial world within us

An overview is presented of the most recent developments and applications of novel culture‐independent approaches that promise to unravel the mechanisms of GI tract functionality and subsequent possibilities to exploit specifically these mechanisms in order to improve gut health.


Resumen es: El metagenoma humano es una composicion de los genes de las celulas eucarioticas del Homo sapiens y los genes presentes en los miles de millones de genom...

An ecological and evolutionary perspective on human–microbe mutualism and disease

The shared evolutionary fate of humans and their symbiotic bacteria has selected for mutualistic interactions that are essential for human health, and ecological or genetic changes that uncouple this shared fate can result in disease.

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GF animals are protected from diet-induced obesity by two complementary but independent mechanisms that result in increased fatty acid metabolism: elevated levels of Fiaf, which induces Pgc-1α; and increased AMPK activity.

An obesity-associated gut microbiome with increased capacity for energy harvest

It is demonstrated through metagenomic and biochemical analyses that changes in the relative abundance of the Bacteroidetes and Firmicutes affect the metabolic potential of the mouse gut microbiota and indicates that the obese microbiome has an increased capacity to harvest energy from the diet.

The gut microbiota as an environmental factor that regulates fat storage.

It is found that conventionalization of adult germ-free (GF) C57BL/6 mice with a normal microbiota harvested from the distal intestine of conventionally raised animals produces a 60% increase in body fat content and insulin resistance within 14 days despite reduced food intake.

Synbiotics, prebiotics, glutamine, or peptide in early enteral nutrition: a randomized study in trauma patients.

Patients supplemented with synbiotics did better than the others, with lower intestinal permeability and fewer infections.

The environment within: how gut microbiota may influence metabolism and body composition

This review discusses the relationships between the following: composition of gut microbiota, energy extracted from diet, synthesis of gut hormones involved in energy homeostasis, production of butyrate and the regulation of fat storage.

Human colonic microbiota associated with diet, obesity and weight loss

Diets designed to achieve weight loss in obese subjects can significantly alter the species composition of the gut microbiota, but there is no evidence that the proportions of Bacteroidetes and Firmicutes among fecal bacteria have a function in human obesity.