Einfluss von Celebrex und Zyflo auf die Lebermetastasierung und die Lipidperoxidation beim Pankreaskarzinom im Syrischen Hamster

@inproceedings{Wenger2002EinflussVC,
  title={Einfluss von Celebrex und Zyflo auf die Lebermetastasierung und die Lipidperoxidation beim Pankreaskarzinom im Syrischen Hamster},
  author={F. Wenger and M. Kilian and I. Mautsch and J. Gregor and C. Kiewert and I. Schimke and H. Guski and J. M{\"u}ller},
  year={2002}
}
Selective inhibition of eicosanoid synthesis is supposed to have effects on carcinogenesis. However, it is still unknown whether pancreatic cancer might be influenced as well. Therefore we evaluated the impact of selective cyclooxygenase-2 inhibitor Celebrex and selective 5-lipoxygenase inhibitor Zyflo on liver metastasis in a solid model of chemically induced pancreatic adenocarcinoma in Syrian hamsters. In week 33 the animals were sacrified and incidence of pancreatic carcinomas and liver… Expand