Eif3ba regulates cranial neural crest development by modulating p53 in zebrafish.

@article{Xia2013Eif3baRC,
  title={Eif3ba regulates cranial neural crest development by modulating p53 in zebrafish.},
  author={Zhidan Xia and Xiangjun Tong and Fang Liang and Yihan Zhang and Chikin Kuok and Yingla Zhang and Xinxing Liu and Z. Zhu and Shuo Lin and Bo Zhang},
  journal={Developmental biology},
  year={2013},
  volume={381 1},
  pages={83-96}
}
Congenital diseases caused by abnormal development of the cranial neural crest usually present craniofacial malformations and heart defects while the precise mechanism is not fully understood. Here, we show that the zebrafish eif3ba mutant caused by pseudo-typed retrovirus insertion exhibited a similar phenotype due to the hypogenesis of cranial neural crest cells (NCCs). The derivatives of cranial NCCs, including the NCC-derived cell population of pharyngeal arches, craniofacial cartilage… CONTINUE READING