Eicosapentaenoic acid and docosahexaenoic acid production potential of microalgae and their heterotrophic growth

@article{Vazhappilly1998EicosapentaenoicAA,
  title={Eicosapentaenoic acid and docosahexaenoic acid production potential of microalgae and their heterotrophic growth},
  author={Rema Vazhappilly and Feng Chen},
  journal={Journal of the American Oil Chemists' Society},
  year={1998},
  volume={75},
  pages={393-397}
}
Twenty microalgal strains were investigated in photoautotrophic flask cultures for their potential for eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) production. The highest EPA proportion (% of total fatty acids) was produced by Monodus subterraneus UTEX 151 (34.2%), followed by Chlorella minutissima UTEX 2341 (31.3%) and Phaeodactylum tricornutum UTEX 642 (21.4%). The highest DHA proportion (% of total fatty acids) was obtained in Crypthecodinium cohnii UTEX L1649 (19.9… Expand

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References

SHOWING 1-10 OF 18 REFERENCES
Screening of algae for potential alternative sources of eicosapentaenoic acid
TLDR
The content of docosahexaenoic acid (DHA) and arachidonic acid, in the best EPA producers was low, or negligible, which has important advantages in simplifying EPA recovery. Expand
Production potential of eicosapentaenoic acid byMonodus subterraneus
TLDR
M. subterraneus is one of the most promising candidates for phototrophic production of EPA and under low light intensity or high biomass concentration enhanced the proportion and content of EPA. Expand
Optimization of production of docosahexaenoic acid (DHA) byThraustochytrium aureum ATCC 34304
TLDR
By varying culture carbon source, lipid content in mycelium of Thraustochytrium aureum ATCC 34304 varied widely in the range 1–25% of biomass weight, which was optimal at an initial culture pH of 6.0. Expand
Culture conditions affect eicosapentaenoic acid content ofChlorella minutissima
Marine chlorella known to contain high amount of eicosapentaenoic acid (20:5ω3) are a potential natural source of this fatty acid for health foods and pharmaceuticals. The effect of cultureExpand
The production potential of eicosapentaenoic and arachidonic acids by the red algaPorphyridium cruentum
TLDR
It was possible to obtain a lipid mixture which may be separated into AA and EPA rich fractions by imposing nitrogen starvation, and high EPA content was obtained under conditions resulting in high growth rate. Expand
Preparation of eicosapentaenoic acid (EPA) concentrate fromPorphyridium cruentum
The polyunsaturated fatty acid eicosapentaenoic acid (EPA) has attracted increased attention due to its pharmaceutical properties. The main source is marine fish oil which contains approximately 15%Expand
Development of an industrial-scale process for the heterotrophic production of a micro-algal mollusc feed
TLDR
Dried Tetraselmis CSL161, sold as Celsys Algal 161, can directly replace live Tetraelmis in bivalve feed and may provide up to 70% replacement for hatchery-grown micro-algae. Expand
Substrate inhibition of Chlamydomonas reinhardtii by acetate in heterotrophic culture
TLDR
The heterotrophic growth of microalgae has been proposed as a potential mode of culture to achieve high cell densities on a large scale and a model based on constant qm was proposed to describe the latter phenomenon but there was significant lack of fit between simulated and experimental data. Expand
EFFECT OF ENVIRONMENTAL CONDITIONS ON FATTY ACID COMPOSITION OF THE RED ALGA PORPHYRIDIUM CRUENTUM: CORRELATION TO GROWTH RATE 1
TLDR
The lipid and fatty acid composition of Porphyridium cruentum was determined as a function of light intensity, temperature, pH, and salinity and the content of eicosapentaenoic acid decreased and that of arachidonic acid increased, the latter becoming the major polyunsaturated fatty acid. Expand
High cell density culture of microalgae in heterotrophic growth
TLDR
High cell density processes suitable for heterotrophic cultures of microalgae may provide an alternative means for the large-scale production of algal products of high value. Expand
...
1
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