Eicosanoids in tumor progression and metastasis.

  title={Eicosanoids in tumor progression and metastasis.},
  author={Sriram Krishnamoorthy and Kenneth V. Honn},
  journal={Sub-cellular biochemistry},
Eicosanoids and the enzymes responsible for their generation in living systems are involved in the mediation of multiple physiological and pathophysiological responses. These bioactive metabolites are part of complex cascades that initiate and perpetuate several disease processes such as atherosclerosis, arthritis, neurodegenerative conditions, and cancer. The intricate role played by each of these metabolites in the initiation, progression, and metastasis of solid tumors has been a subject of… CONTINUE READING

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