Eicosanoids and the hemodynamic course of live Escherichia coli-induced sepsis in baboons.

@article{Camporesi1989EicosanoidsAT,
  title={Eicosanoids and the hemodynamic course of live Escherichia coli-induced sepsis in baboons.},
  author={Enrico Mario Camporesi and Shinobu Oda and Philip Fracica and Jeffery Griebel and J E Shook and Claude A. Piantadosi and Wynell Watkins},
  journal={Circulatory shock},
  year={1989},
  volume={29 3},
  pages={229-44}
}
Time-related changes in eicosanoid release and hemodynamic parameters were characterized in baboons during the early development of sepsis induced by intravenous (i.v.) infusion of live Escherichia coli (4 x 10(10) organisms/kg) in baboons. Plasma levels of thromboxane B2 (TxB2), a stable metabolite of thromboxane A2 (TxA2), rose rapidly in arterial, venous, and pulmonary arterial blood after infusion of live E. coli, attaining maximal increases at 30 min and returning to control values by 60… CONTINUE READING