Corpus ID: 10808311

Eicosanoid synthesis by cultured human urothelial cells: potential role in bladder cancer.

@article{Danon1986EicosanoidSB,
  title={Eicosanoid synthesis by cultured human urothelial cells: potential role in bladder cancer.},
  author={A. Danon and T. Zenser and D. Thomasson and B. Davis},
  journal={Cancer research},
  year={1986},
  volume={46 11},
  pages={
          5676-81
        }
}
Prostaglandin (PG) H synthase and eicosanoid products of arachidonic acid metabolism have been implicated in several steps in the carcinogenic process. This study assessed these parameters using primary cultures of human urothelial cells. To determine the possible presence of permeability barriers to agonist stimulation, incubations were performed with adherent cells in the presence or absence of thioglycolate pretreatment or with cell suspensions. No evidence for permeability barriers was… Expand
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