Eicosanoid production by peritoneal and splenic macrophages in mice depleted of bone marrow by 89Sr.

@article{Shibata1987EicosanoidPB,
  title={Eicosanoid production by peritoneal and splenic macrophages in mice depleted of bone marrow by 89Sr.},
  author={Yoshisada Shibata and Abraham P Bautista and Sam N Pennington and John L Humes and Alvin Volkman},
  journal={The American journal of pathology},
  year={1987},
  volume={127 1},
  pages={75-82}
}
Previous studies showed that the prostaglandin-forming macrophages (M phi) induced in the spleens of CBA/J mice by intraperitoneal administration of Corynebacterium parvum (CP) could not be demonstrated following the depletion of bone marrow and blood monocytes with 89Sr. The present study compares prostaglandin E2 (PGE2), leukotriene C4 (LTC4), and LTB4 release by splenic and resident peritoneal M phi in 89Sr-treated mice and 88Sr controls following in vivo CP and in vitro incubation with… CONTINUE READING
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