Egr-1 is a Major Vascular Pathogenic Transcription Factor in Atherosclerosis and Restenosis

@article{Blaschke2004Egr1IA,
  title={Egr-1 is a Major Vascular Pathogenic Transcription Factor in Atherosclerosis and Restenosis},
  author={F. Blaschke and D. Bruemmer and R. Law},
  journal={Reviews in Endocrine and Metabolic Disorders},
  year={2004},
  volume={5},
  pages={249-254}
}
The zinc finger transcription factor Egr-1 (early growth response factor-1), also known as nerve growth factorinduced-A (NGFI-A), zif268, Krox-24 and TIS8 was first identified by Sukhatme and colleagues [1]. It is the prototype of a family of zinc-finger transcription factors, that includes Egr-2, Egr-3 and Egr-4. Egr-1 is rapidly and transiently expressed in many different cell types in response to a variety of extracellular stimuli, including growth factors, cytokines and injurious stimuli [2… Expand
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