Efflux pumps in drug resistance of Candida.

  title={Efflux pumps in drug resistance of Candida.},
  author={Rajendra Prasad and Naseem A Gaur and Manisha Gaur and Sneha Sudha Komath},
  journal={Infectious disorders drug targets},
  volume={6 2},
The incidences of human pathogenic yeast Candida albicans and its related species acquiring resistance to antifungals have increased considerably, which poses serious problems towards its successful chemotherapy. The resistance of these pathogenic fungi is not restricted to the commonly used triazole compounds but is even encountered, though not often, with polyene derivatives as well. The efflux pump proteins belonging to ABC (ATP Binding Cassette) and MFS (Major Facilitators) super family are… CONTINUE READING
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